GABAAreseptoreiden
GABAA receptors are a class of ionotropic receptors that are the primary targets for the neurotransmitter gamma-aminobutyric acid (GABA). These receptors are pentameric proteins composed of five subunits, each of which is a ligand-gated ion channel. The most common subunit is the alpha subunit, which has multiple isoforms (alpha1 to alpha6). The beta, gamma, delta, epsilon, theta, and pi subunits also contribute to the receptor's structure and function.
GABAA receptors are widely distributed throughout the central and peripheral nervous systems, where they mediate inhibitory
GABAA receptors are also targets for several clinically important drugs, such as benzodiazepines and barbiturates, which
Mutations in the genes encoding GABAA receptor subunits have been associated with several neurological disorders, including