Frizzledlike
Frizzledlike is a protein that belongs to the Frizzled family of receptor tyrosine kinases, which are involved in signal transduction in various organisms. It is primarily expressed in the developing nervous system and is crucial for the development of the brain and spinal cord. The Frizzledlike protein is a key component in the Wnt signaling pathway, which plays a significant role in cell fate determination, tissue patterning, and morphogenesis.
The Frizzledlike protein is named after its structural similarity to the Frizzled receptor, which is a well-known
Mutations in the FZD-like gene, which encodes Frizzledlike, have been linked to various neurological disorders, including
In addition to its role in neurological development, Frizzledlike is also expressed in other tissues, such