Fibroideja

Fibroideja is a term used in medical literature to describe a group of benign lesions characterized by the proliferation of fibrous connective tissue. In some contexts the term is used interchangeably with fibroma or with certain soft-tissue tumors of fibroblastic origin; its exact usage can vary by country and specialty.

Pathology and histology: Lesions range from well-circumscribed to mildly infiltrative. Microscopically they consist of spindle-shaped fibroblasts in a collagen-rich stroma, with sparse mitotic activity and little cellular atypia. Some variants show myofibroblastic differentiation and may express smooth muscle actin; immunoprofiles typically include vimentin positivity.

Clinical features: Fibroidejas typically present as slow-growing, painless nodules or masses. They arise in soft tissues such as the skin, subcutaneous tissue, or mucosa, including the oral cavity. They are usually small, but can vary in size depending on location. The clinical differential includes other fibrous lesions and soft-tissue tumors.

Diagnosis and treatment: Diagnosis is made by histopathological examination after biopsy or excisional removal. Treatment is usually surgical excision with clear margins. Recurrence is possible but uncommon in many fibrous lesions; some infiltrative variants have higher recurrence risk.

Prognosis and terminology: Prognosis is generally favorable after complete removal. The term fibroideja is regional; in some settings lesions are termed fibromas or fibrous tumors depending on histology and site. Ongoing classification reflects differences in growth pattern and cellularity.

See also: fibroma; fibrous dysplasia; soft-tissue tumor.