Farmakokinetyczny

Farmakokinetyczny describes the processes that a drug undergoes within the body. It is a fundamental concept in pharmacology that essentially asks what the body does to the drug. The term encompasses four main processes: absorption, distribution, metabolism, and excretion, often referred to by the acronym ADME. Absorption is how a drug enters the bloodstream from its administration site. Distribution is how the drug moves throughout the body's tissues and fluids. Metabolism refers to the chemical transformation of the drug by the body, often by enzymes, which can lead to inactivation or activation of the drug. Finally, excretion is the removal of the drug and its metabolites from the body, typically through the kidneys or liver. Understanding the farmakokinetyczny profile of a drug is crucial for determining appropriate dosage, frequency of administration, and potential drug interactions. It helps predict how much of a drug will reach its target site and how long it will remain in the body, influencing therapeutic efficacy and safety. Factors such as age, disease state, and genetics can significantly impact a drug's farmakokinetyczny behavior.