FVIIIn
FVIIIn is a hypothetical protein that has not been experimentally characterized or identified in scientific literature. The designation FVIIIn suggests it might be a variant, isoform, or a related protein to Factor VII, a coagulation factor. Factor VII is a vitamin K-dependent protein synthesized in the liver that plays a crucial role in the extrinsic pathway of the blood coagulation cascade. It is activated by Factor VIIa, which then converts Factor X to Factor Xa and Factor IX to Factor IXa, initiating the common pathway of coagulation.
Given the nomenclature, FVIIIn could potentially represent a naturally occurring splice variant of the Factor VII