FIB4index

The FIB-4 index is a scoring system used to predict the risk of significant fibrosis in patients with chronic hepatitis C or non-alcoholic fatty liver disease (NAFLD). It was developed by the European Association for the Study of the Liver (EASL) and is based on four easily obtainable laboratory parameters: age, aspartate aminotransferase (AST) to platelet ratio index (APRI), alanine aminotransferase (ALT) to platelet ratio index (ALPRI), and gamma-glutamyl transferase (GGT). The index is calculated by assigning points to each parameter based on predefined cutoffs, and the total score is used to categorize the risk of significant fibrosis. A score of 0-1 indicates low risk, 2-3 indicates intermediate risk, and 4-6 indicates high risk. The FIB-4 index has been validated in multiple studies and has shown good performance in predicting significant fibrosis. However, it is not a diagnostic tool and should be used in conjunction with other clinical and laboratory findings. The FIB-4 index is a useful tool for identifying patients at high risk of significant fibrosis who may benefit from further evaluation and potential treatment.