FGF3

FGF3, also known as Fibroblast Growth Factor 3, is a protein-encoded gene found in humans. This gene is part of the fibroblast growth factor family, which plays a crucial role in various biological processes including cell growth, differentiation, and migration. FGF3 specifically is involved in the development of the inner ear and the formation of the placenta. It is a secreted protein, meaning it can act on cells outside of where it is produced.

Research has indicated that FGF3 is important for the proper development of the cochlea, a part of the inner ear responsible for hearing. Mutations in the FGF3 gene have been linked to certain types of hearing loss. Furthermore, FGF3 has a role in embryonic development, particularly in the formation and function of the placenta, which provides nutrients and oxygen to the developing fetus. Aberrant FGF3 signaling has also been implicated in certain types of cancer, where it can promote tumor growth and invasion. The precise mechanisms by which FGF3 exerts its effects are still under active investigation, but it is known to interact with specific receptor proteins on the surface of target cells to initiate signaling pathways.