Exalgo
Exalgo is a brand name for an extended-release formulation of hydromorphone hydrochloride, an opioid analgesic used for the management of moderate to severe chronic pain in adults who are opioid-tolerant and require around-the-clock analgesia. It is intended for long-term pain control and is administered orally on a once-daily basis.
The product is designed with an abuse-deterrent formulation intended to resist crushing and injection, while preserving
Exalgo is available in 8 mg, 16 mg, and 32 mg extended-release tablets. The recommended starting dose
Contraindications include significant respiratory depression, acute or severe bronchial asthma without adequate monitoring, known hypersensitivity to
Pharmacologically, hydromorphone is a mu-opioid receptor agonist. It is metabolized to hydromorphone-3-glucuronide and primarily excreted renally.