Ethanesulfonyl

Ethanesulfonyl refers to the functional group with the chemical formula CH3CH2SO2-. It is derived from ethane and contains a sulfonyl group (SO2). This group is characterized by a sulfur atom double-bonded to two oxygen atoms and single-bonded to two other atoms or groups. In the case of ethanesulfonyl, the sulfur atom is bonded to an ethyl group (CH3CH2-) and, typically, another atom or group, forming a sulfone or sulfonate ester.

Ethanesulfonyl groups are found in various organic compounds and play a role in their chemical properties and reactivity. For example, ethanesulfonyl chloride (CH3CH2SO2Cl) is a reactive intermediate used in organic synthesis to introduce the ethanesulfonyl group into other molecules. Ethanesulfonamides (CH3CH2SO2NR2), where R represents hydrogen or an organic group, are a class of compounds that contain the ethanesulfonyl moiety attached to a nitrogen atom. Some drugs and biologically active molecules incorporate the ethanesulfonyl group, influencing their interactions with biological targets. The presence of the electron-withdrawing sulfonyl group can affect the acidity of adjacent protons and the overall polarity of the molecule.