Electrogenic
Electrogenic refers to processes or transports in biological systems that generate or contribute to an electrical potential across a membrane by moving a net charge. In physiology, an electrogenic transporter or pump creates an electrical current or alters the membrane potential by transferring more positive charges in one direction than in the opposite direction.
- Na+/K+-ATPase, which exports three Na+ ions and imports two K+ ions with each ATP hydrolyzed, generating
- Proton pumps such as H+-ATPase in plant, fungal, and some bacterial membranes, which move H+ ions
- Electrogenic cotransporters like the Na+-glucose cotransporter (SGLT) in intestinal and renal epithelia, which move Na+ and
Electrogenicity also underpins barriers and transport in many tissues. In neurons and muscle cells, electrogenic pumps
Not all ion movements are electrogenic; some transporters move ions in a way that balances charge across