EV71n

EV71n refers to a specific genotype of Enterovirus 71 (EV-A71), a virus belonging to the Enterovirus genus of the Picornaviridae family. Enteroviruses are a group of small, non-enveloped RNA viruses that are commonly found in the gastrointestinal tract of humans. EV-A71 is a significant human pathogen, primarily known for causing hand, foot, and mouth disease (HFMD), a contagious illness that typically affects infants and young children. While HFMD is usually mild and self-limiting, EV-A71 can, in some cases, lead to severe neurological complications such as aseptic meningitis, encephalitis, and even acute flaccid paralysis, which can be fatal.

Genotypes are used to classify strains of a virus based on genetic differences, particularly in their surface proteins. The classification of EV-A71 into various genotypes, including EV71n, helps in understanding its epidemiological patterns, evolutionary history, and potential for causing outbreaks. Different genotypes can exhibit variations in their virulence, transmissibility, and geographical distribution. The study of EV71n, like other genotypes, is crucial for developing effective diagnostic tools, antiviral therapies, and vaccines to control and prevent EV-A71 infections. Research into specific genotypes assists public health officials in monitoring the spread of the virus and implementing targeted control measures.