ENCK2

ENCK2, also known as Encephalopsin 2 or Opn3b, is a protein encoded by the OPN3 gene in zebrafish. It is a member of the opsin family of proteins, which are light-sensitive proteins found in the eyes and other tissues. ENCK2 is specifically a type of non-visual opsin, meaning it is not primarily involved in vision but rather in other light-dependent processes.

ENCK2 is expressed in various tissues in zebrafish, including the brain, pineal gland, and retina. Its exact function is not yet fully understood, but research suggests it may play a role in the regulation of circadian rhythms, which are the internal biological clocks that govern various physiological processes. The protein has been shown to respond to light stimuli, potentially influencing the body's response to environmental light changes.

Studies on ENCK2 have primarily been conducted in zebrafish, a model organism widely used in biological and medical research. These studies have provided insights into the molecular mechanisms underlying light-dependent processes in non-mammalian vertebrates. The findings may have implications for understanding similar processes in other species, including humans, where non-visual opsins also play crucial roles.

Further research is needed to fully elucidate the function of ENCK2 and its potential implications for human health. Understanding the role of non-visual opsins like ENCK2 could contribute to the development of therapies for disorders related to circadian rhythm disruptions, such as sleep disorders and mood disorders.