Dadénosine

Dadénosine, also known as deoxyadenosine, is a nucleoside composed of adenine base and a deoxyribose sugar. It is a component of deoxyribonucleic acid (DNA), where it pairs with thymine through hydrogen bonding. Dadénosine is formed by the removal of the 3'-hydroxyl group from adenosine, which is a nucleoside found in ribonucleic acid (RNA). The deoxyribose sugar in dadénosine lacks the hydroxyl group at the 2' position, which distinguishes it from the ribose sugar found in adenosine. This structural difference is crucial for the stability and function of DNA, as it prevents the formation of a 2'-5' phosphodiester bond, which is not present in DNA. Dadénosine is synthesized through the action of enzymes such as deoxyribonucleoside triphosphate nucleotidohydrolases, which catalyze the removal of the 3'-hydroxyl group from adenosine. It is an important building block in the synthesis of DNA and plays a vital role in genetic information storage and transmission.