Cterminaalne
C-terminaalne, or C-terminus, refers to the end of a protein or polypeptide that carries the free carboxyl group. It is opposite the N-terminus, which bears the amino group. Proteins are synthesized from the N-terminus to the C-terminus, and the C-terminal region often influences function, stability, and interactions, either on its own or through post-translational modifications.
The C-terminus can contain signals that determine cellular localization. For example, the peroxisomal targeting signal type
Post-translational modifications and processing often affect the C-terminus. C-terminal amidation is a common modification in neuropeptides
In research and bioinformatics, the C-terminus is used to classify protein families, identify functional motifs, and