Chlorosulfonates
Chlorosulfonates are chemical compounds in which a sulfonyl chloride group (-SO2Cl) is bound to an alkoxy or aryl fragment, giving alkyl or aryl chlorosulfonates with the general structure R-O-SO2-Cl. Common examples include methyl chlorosulfonate and ethyl chlorosulfonate. They are often considered activated sulfonylating agents used in organic synthesis.
Preparation of chlorosulfonates typically involves the reaction of an alcohol with chlorosulfonyl chloride (ClSO2Cl) in an
Properties of chlorosulfonates include high reactivity and instability in the presence of water or protic solvents.
Applications of chlorosulfonates center on their role as activated sulfonylating agents. They facilitate the formation of