ChalconeSynthase
Chalcone synthase (CHS) is a plant enzyme that catalyzes the first committed step in the biosynthesis of flavonoids. It belongs to the type III polyketide synthase family and typically forms homodimers of about 42–45 kDa, with subunits of roughly 389 amino acids. CHS is widely studied in flowering plants, where multiple CHS genes may be present.
CHS catalyzes the condensation of one molecule of p-coumaroyl-CoA with three molecules of malonyl-CoA to yield
Genetic and regulatory aspects: CHS genes are often developmentally regulated and respond to light, UV exposure,
Significance and applications: CHS is a key control point in flavonoid biosynthesis, influencing flower color, pollen