CSNK1G13

CSNK1G13, also known as Casein kinase I gamma 13, is a protein-coding gene in humans that encodes a member of the casein kinase I gamma (CK1G) subfamily of serine/threonine kinases. CK1 gamma enzymes are constitutively active kinases involved in phosphorylation of a wide range of substrates, influencing signaling pathways such as Wnt signaling, vesicle trafficking, and circadian rhythm regulation.

The specific substrate repertoire and biological roles of CSNK1G13 have not been extensively characterized; current knowledge primarily places it within the CK1 gamma family, with the implication that it participates in cellular signaling at the cytoplasm and possibly at membranes.

Expression data are limited; CSNK1G13 appears to be expressed in multiple tissues, but detailed tissue distribution and expression levels require confirmation from transcriptomic datasets.

Genomic and proteomic resources (for example NCBI Gene, Ensembl, UniProt) provide entries for CSNK1G13 and note it as a kinase; there are no well-established disease associations linked specifically to CSNK1G13 to date.

As with many members of the CK1 family, further research is needed to define its precise functions, substrates, and physiological relevance.