CNScentered

CNScentered is a term used in neuroscience and clinical practice to describe an approach that centers the central nervous system (CNS) in the study, diagnosis, and treatment of neurological and psychiatric conditions. While not tied to a single organization, the term has appeared in academic discussions and some clinical theses as a contrast to models that emphasize peripheral systems or systemic factors.

Core concept: CNScentered thinking prioritizes CNS pathophysiology, including brain and spinal cord structure and function, neurotransmitter dynamics, neuroinflammation, and neural networks. It relies on CNS-focused diagnostics such as neuroimaging, EEG/MEG, and CSF biomarkers, and it favors interventions aimed at CNS targets, including pharmacotherapy, neuromodulation, and neurorehabilitation.

Applications: In clinical practice, CNScentered approaches guide assessment toward CNS etiologies of symptoms and prioritize CNS-directed treatments. In research, it encourages trials that assess CNS outcomes and mechanisms. In education, it frames curricula around CNS mechanisms and CNS-acting therapies.

Criticisms and limitations: Critics argue that exclusively CNS-centered models risk neglecting peripheral contributors, psychosocial and environmental factors, and systemic comorbidities that influence CNS disease. Proponents stress integrating CNS-centered insights with holistic care.

See also: central nervous system, neurocentrism, neuroimaging, neuromodulation, neurobiology.