CNOT2

CNOT2, also known as DEPDC1B, is a protein-coding gene that plays a role in transcriptional regulation. It is a component of the general transcription factor TFIID complex, which is essential for the initiation of transcription by RNA polymerase II. The CNOT2 protein is involved in the assembly and function of this complex, interacting with other subunits to ensure accurate and efficient gene expression. Research suggests that CNOT2 may also participate in other cellular processes, although its precise functions beyond transcription are still being investigated. Mutations or altered expression levels of CNOT2 have been linked to certain diseases, including some types of cancer, where dysregulation of gene expression can have significant consequences. Understanding the role of CNOT2 is crucial for unraveling the complexities of gene regulation and its impact on cellular health and disease.