CHIKVneutralization
CHIKV neutralization refers to the process by which the infectivity of the Chikungunya virus (CHIKV) is blocked. This is primarily achieved through the action of antibodies. When an individual is infected with CHIKV, their immune system generates specific antibodies that can bind to the virus. This binding can interfere with the virus's ability to attach to host cells or to enter them, thereby preventing or significantly reducing infection.
Neutralizing antibodies can target various parts of the CHIKV virion, most commonly the E1 and E2 glycoproteins
The effectiveness of CHIKV neutralization is a key factor in determining the outcome of infection and the