CDNP2P

CDNP2P, also known as Cyclin D-binding protein 1, is a protein encoded by the CDNP2P gene in humans. This gene is located on chromosome 7. The protein it produces plays a role in cell cycle regulation, specifically in the G1 to S phase transition. It is known to interact with Cyclin D, a key component of cyclin-dependent kinases (CDKs) that drive cell proliferation.

The precise mechanisms by which CDNP2P influences the cell cycle are still under investigation. However, it is believed to act as a scaffolding protein, facilitating the assembly and function of Cyclin D-CDK complexes. This interaction is crucial for the phosphorylation of retinoblastoma protein (Rb), which in turn releases transcription factors necessary for DNA replication and cell division. Alterations in CDNP2P expression or function have been implicated in certain types of cancer, suggesting its potential role in tumorigenesis and progression. Research continues to explore its involvement in normal cellular processes and its implications in disease states, potentially leading to therapeutic targets.

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