CCR5tä

CCR5tä is a term that refers to a specific genetic variation, or allele, of the CCR5 gene. The CCR5 gene provides instructions for making a receptor protein that is found on the surface of white blood cells. This receptor plays a crucial role in the immune system, particularly in the body's response to inflammation and infection. It is also known to be a co-receptor used by certain viruses, most notably the human immunodeficiency virus (HIV), to enter host cells.

The "tä" designation typically indicates a specific mutation or a non-standard variant of the CCR5 gene. While the most well-known variant is CCR5-delta 32 (CCR5-Δ32), which confers resistance to certain strains of HIV, the "tä" notation might refer to other, less common or newly identified variations. Understanding these variations is important in research related to infectious diseases and immunology. Genetic studies often investigate the presence and effects of such alleles to understand individual susceptibility or resistance to diseases and to explore potential therapeutic targets. The precise biological significance and prevalence of a specific "CCR5tä" allele would depend on the exact genetic change it represents.