CCR5delta32
CCR5delta32 is a specific genetic mutation that affects the CCR5 gene. This gene provides instructions for making a protein that acts as a receptor on the surface of certain white blood cells. This receptor plays a crucial role in the immune system, particularly in how certain types of white blood cells travel to sites of infection and inflammation.
The delta32 mutation involves a deletion of 32 base pairs within the CCR5 gene. Individuals who inherit
The CCR5delta32 mutation is more prevalent in populations of European descent. Its discovery has been significant