C14H14N3NaO3S

C14H14N3NaO3S is the chemical formula for Sodium Metamisole, also known as Metamizole Sodium. It is a synthetic pyrazolone derivative and a non-steroidal anti-inflammatory drug (NSAID). This compound is primarily used for its analgesic and antipyretic properties. It is effective in managing moderate to severe pain and fever.

Sodium Metamisole acts by inhibiting cyclooxygenase (COX) enzymes, which are involved in the synthesis of prostaglandins, mediators of pain and fever. It is administered orally, intravenously, or intramuscularly, depending on the clinical situation and the desired speed of action. The drug's efficacy is well-documented in various pain conditions, including postoperative pain, colic, and cancer-related pain.

While widely used in many countries, Sodium Metamisole is not approved in some regions, such as the United States, due to concerns about potential side effects, particularly agranulocytosis, a serious condition characterized by a severe drop in white blood cell count. Other reported side effects include allergic reactions, skin rashes, and gastrointestinal disturbances. Due to these risks, its use is often restricted to situations where other analgesics are ineffective or contraindicated. Regulatory bodies and healthcare professionals carefully weigh the benefits against the potential risks when prescribing this medication.