Bufadienolidebased
Bufadienolidebased refers to compounds that are structurally derived from bufadienolide. Bufadienolides are a class of naturally occurring cardiac glycosides characterized by a six-membered lactone ring fused to a steroid nucleus. These compounds are primarily found in plants of the families Crassulaceae and Liliaceae, as well as in the skin secretions of toads belonging to the genus Bufo.
The fundamental structure of a bufadienolide includes a steroidal skeleton with a characteristic unsaturated lactone ring
Bufadienolidebased compounds are known for their potent effects on the cardiovascular system. They act by inhibiting