Bioprozessführung

Bioprozessführung refers to the control and management of biological processes, typically in a controlled environment such as a bioreactor. It encompasses the monitoring and adjustment of various parameters to ensure optimal conditions for the growth and productivity of microorganisms or cells. Key parameters that are controlled include temperature, pH, dissolved oxygen levels, nutrient supply, and agitation. The goal of effective bioprozessführung is to maximize product yield, maintain product quality, and ensure process reproducibility and scalability.

This field integrates principles from biology, chemistry, and engineering. It is crucial for the industrial production of a wide range of products, including pharmaceuticals like antibodies and vaccines, enzymes, biofuels, and food ingredients. Sophisticated control systems, often utilizing sensors and automated feedback loops, are employed to maintain precise environmental conditions. Troubleshooting and optimization are continuous aspects of bioprozessführung, aiming to enhance efficiency and economic viability. Advanced techniques in process analytical technology (PAT) are increasingly used to provide real-time insights into the bioprocess, enabling more dynamic and responsive control strategies. The understanding and mastery of bioprozessführung are therefore fundamental to the success of biotechnology and biopharmaceutical manufacturing.