Avil1

Avil1, also known as A-VIL1 or simply Avil, is a protein encoded by the AVIL gene. This gene is found in humans and many other organisms, suggesting a conserved biological function. Avil1 is a member of the villin gene family, which are known for their roles in actin cytoskeleton organization and dynamics. Proteins in this family are typically involved in the regulation of actin filament branching, capping, and severing.

The Avil1 protein itself is characterized by several distinct domains. These include an N-terminal actin-binding domain and several tandem repeats that are also involved in actin interaction. Its precise cellular localization and function are subjects of ongoing research, but it is believed to play a role in cellular processes that require significant remodeling of the actin cytoskeleton, such as cell migration, cytokinesis, and cell shape maintenance. Aberrant expression or mutations in the AVIL gene have been linked to certain human diseases, although the specific associations are still being investigated. Understanding Avil1's molecular mechanisms could provide insights into cellular biology and potential therapeutic targets for related conditions.