APBB3

APBB3, also known as Amyloid Beta Precursor Protein B3 or APP-binding protein 3, is a protein encoded by the APBB3 gene. This gene is part of the amyloid precursor protein (APP) family, which plays a role in the development of Alzheimer's disease. APBB3 is a member of the APP-binding protein family and is characterized by the presence of a phosphotyrosine-binding domain, a PDZ domain, and a DNA-binding domain. These domains suggest APBB3 interacts with various cellular components and may be involved in signal transduction pathways and gene regulation.

The exact function of APBB3 in the human body is still being investigated. However, research indicates it is involved in the development and function of the central nervous system. It has been observed to interact with APP and other proteins, potentially influencing APP processing and amyloid beta peptide formation. Aberrant processing of APP is a key feature of Alzheimer's disease, leading to the accumulation of toxic amyloid plaques. Therefore, APBB3 is considered a potential candidate in the study of neurodegenerative disorders. Its precise role in disease pathogenesis and potential as a therapeutic target remains an active area of scientific inquiry.