AGO7

AGO7 (Argonaute 7) is a protein found in plants that plays a crucial role in the regulation of gene expression. It is part of the Argonaute protein family, which are key components of RNA silencing pathways, including the microRNA (miRNA) and small interfering RNA (siRNA) pathways. AGO7 is specifically known for its involvement in the biogenesis and function of a particular class of small RNAs that regulate developmental processes in plants.

In plants, AGO7 is essential for the development of the reproductive organs, particularly the formation of ovules within the ovary. It interacts with specific miRNAs that target messenger RNAs (mRNAs) involved in ovule development. By binding to these miRNAs, AGO7 guides them to their target mRNAs, leading to their degradation or translational repression. This precise control of gene expression is vital for ensuring the correct structure and function of ovules, which are precursors to seeds. Mutations in AGO7 can lead to severe defects in ovule development, often resulting in sterility. Research into AGO7 has provided valuable insights into the complex regulatory networks that govern plant reproduction.