ADGRG1

ADGRG1, also known as GPR64 or CXorf23, is a gene that encodes a protein belonging to the adhesion G protein-coupled receptor family. These receptors are characterized by a large extracellular N-terminus that contains a GPS (G protein-coupled receptor proteolytic site) domain. The ADGRG1 protein is a transmembrane receptor, meaning it spans the cell membrane and plays a role in cell-to-cell and cell-to-extracellular matrix interactions.

The ADGRG1 protein is believed to function in various biological processes, including cell adhesion, migration, and signaling. Its precise functions are still under investigation, but it has been implicated in the development and maintenance of certain tissues. Research suggests ADGRG1 may be involved in the central nervous system, bone development, and potentially in immune responses. Dysregulation or mutations in the ADGRG1 gene have been associated with certain genetic disorders, though the exact mechanisms are not fully understood. Further research is ongoing to elucidate the full spectrum of ADGRG1's roles in health and disease.