ADGRG1s

ADGRG1s, also known as Adhesion G protein-coupled receptor G1, is a human gene that encodes a protein belonging to the adhesion G protein-coupled receptor family. These receptors are characterized by an extended extracellular N-terminal domain that contains a hormone-binding motif and a GPCR proteolytic site (GPS) domain. ADGRG1s is a transmembrane protein that plays a role in cell adhesion and signaling. It is expressed in various tissues, including the brain, kidney, and lung. The protein is thought to be involved in developmental processes and tissue homeostasis. Dysregulation of ADGRG1s has been implicated in certain diseases, although specific roles are still under investigation. Research into ADGRG1s aims to elucidate its precise functions in normal physiology and its contribution to pathological conditions. Further studies are ongoing to understand its molecular mechanisms and potential therapeutic targeting.