ACEHemmereingenommene

ACEHemmereingenommene is a German neologism used in some texts to refer to individuals who have taken ACE inhibitors (ACE-Hemmer). The term is not established in formal medical nomenclature but appears in discussions or patient-focused literature as a shorthand for patients treated with ACE inhibitors.

ACE inhibitors are a class of antihypertensive and cardioprotective drugs that block the angiotensin-converting enzyme, reducing production of angiotensin II and aldosterone. This leads to vasodilation, lower blood pressure, and decreased salt and water retention. Indications include essential hypertension, heart failure with reduced ejection fraction, post-myocardial infarction, and diabetic nephropathy.

Clinical use requires consideration of contraindications and safety monitoring. Pregnancy is a clear contraindication; bilateral renal artery stenosis and significant renovascular disease are cautions. Before and during treatment, kidney function and serum potassium should be checked due to risks of hyperkalemia and reduced renal function; there is a risk of angioedema, especially in certain ethnic groups.

Common adverse effects include cough, dizziness, fatigue, and hyperkalemia. Interactions include NSAIDs, which can lessen renal perfusion and antihypertensive effects; potassium-sparing diuretics or supplements may raise potassium levels; disabling interactions with other renin–angiotensin system inhibitors may occur.

Historical context notes that the first ACE inhibitors were developed in the 1980s, with captopril and later enalapril and others becoming standard therapy. The term ACEHemmereingenommene, while not official, captures the subset of patients currently using this drug class.