ACE2reseptoria

ACE2reseptoria refers to the receptor protein Angiotensin-Converting Enzyme 2, often abbreviated as ACE2. This protein is primarily found on the surface of cells in various human tissues, including the lungs, heart, blood vessels, kidneys, and intestines. Its natural biological function is crucial for regulating blood pressure and fluid balance within the body as part of the renin-angiotensin-aldosterone system. ACE2 acts as an enzyme that breaks down angiotensin II, a peptide that can constrict blood vessels and increase blood pressure, into angiotensin (1-7), which has opposite, vasodilatory effects.

Significantly, ACE2 gained widespread attention as the primary cellular receptor used by the SARS-CoV-2 virus, the causative agent of COVID-19, to enter human cells. The spike protein on the surface of SARS-CoV-2 binds to the ACE2 receptor, facilitating viral entry and subsequent infection. This interaction has made ACE2 a focal point of research into viral pathogenesis and potential therapeutic strategies for COVID-19. Understanding the structure and function of ACE2, as well as its interaction with viral proteins, is vital for developing vaccines and antiviral treatments. Research continues to explore the diverse roles of ACE2 beyond its interaction with SARS-CoV-2 and its implications in various physiological and pathological conditions.