8p211

8p211 refers to a specific location on the short arm of human chromosome 8. The "8p" denotes chromosome 8, short arm, and "211" is a band designation within that region, following standard cytogenetic nomenclature. This chromosomal region can be involved in various genetic alterations, including deletions, duplications, translocations, and inversions. These structural changes can disrupt genes located within or near the 8p211 locus, potentially leading to a range of phenotypic effects. The specific consequences depend on the precise nature of the alteration and which genes are affected. Research into this region has identified genes with diverse functions, some of which have been implicated in developmental disorders or certain types of cancer. For instance, abnormalities in chromosome 8, including this specific region, have been noted in some hematological malignancies. Further investigation is often required to understand the precise impact of any given alteration within 8p211 on an individual's health. Genetic testing, such as chromosomal microarray or karyotyping, is used to identify structural variations at this locus.