4thiouridinebased
4thiouridine is a modified nucleoside that is a derivative of uridine. In this molecule, the oxygen atom at the 4-position of the uracil base is replaced by a sulfur atom. This substitution significantly alters the electronic and chemical properties of the nucleoside. Specifically, the presence of sulfur makes 4thiouridine more susceptible to photochemical reactions, particularly when exposed to ultraviolet (UV) light.
This photosensitivity has made 4thiouridine a valuable tool in molecular biology research. When incorporated into RNA,