4iodophenol

4-iodophenol, also known as para-iodophenol or p-iodophenol, is an organoiodine compound with the formula C6H5IO. It consists of a benzene ring bearing a hydroxyl group and an iodine substituent in the para position relative to the hydroxyl group.

The compound typically appears as a colorless to white crystalline solid. It is sparingly soluble in water and more soluble in many organic solvents such as ethanol and ether.

4-iodophenol is not naturally occurring. It is produced commercially by iodination of phenol or via related halogenation routes. It serves as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and dyes, and can be converted into other iodine-containing derivatives.

Chemically, the presence of the phenolic OH group allows formation of phenoxide salts under basic conditions, while the iodine substituent provides a versatile handle for cross-coupling reactions and other transformations after protection or activation of the phenol. This makes 4-iodophenol a useful starting material in organic synthesis.

Safety and handling: 4-iodophenol is an irritant and should be handled with appropriate personal protective equipment. It may cause skin and eye irritation and can release iodine-containing vapors; store away from oxidizers and in a well-ventilated area.