4Pyridinol

4-Pyridinol, also known as 4-hydroxypyridine, is an organic compound with the chemical formula C5H5NO. It is a derivative of pyridine, where a hydroxyl group is attached to the carbon atom at the 4-position of the pyridine ring. At room temperature, 4-pyridinol exists as a solid. It exhibits tautomerism, meaning it can exist in equilibrium with its keto tautomer, 4-pyridone. This phenomenon influences its chemical properties and reactivity.

The synthesis of 4-pyridinol can be achieved through various chemical routes. One common method involves the hydrolysis of 4-halopyridines. It is also a byproduct in some industrial processes.

4-Pyridinol is soluble in water and polar organic solvents. Its chemical behavior is characterized by the presence of both the aromatic pyridine ring and the hydroxyl group. It can undergo reactions typical of phenols, such as etherification and esterification, as well as reactions characteristic of pyridine, such as N-alkylation. The compound can act as a weak acid due to the hydroxyl group.

In terms of applications, 4-pyridinol serves as a building block or intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. Its derivatives have shown biological activity and are explored for medicinal purposes. Due to its tautomeric nature and reactivity, it is a valuable molecule in organic chemistry research and development.