4Ethoxyaniline

4-Ethoxyaniline, also known as p-ethoxyaniline, is an aromatic amine in which a para ethoxy group is attached to the aniline ring. Its molecular formula is C8H11NO, reflecting a benzene ring bearing an amino group (NH2) and an ethoxy substituent (OCH2CH3) at opposite positions.

Synthesis and uses: 4-Ethoxyaniline can be prepared by O-ethylation of 4-aminophenol, which converts the phenolic OH into an ethoxy group while leaving the amino group intact. It is primarily employed as a chemical building block in organic synthesis, notably in the preparation of azo dyes and related pigment systems. It also serves as an intermediate in the manufacture of certain pharmaceutical and agrochemical compounds and other specialty chemicals.

Properties and behavior: As an aniline derivative, 4-ethoxyaniline is typically basic and participates in standard amine chemistry, including diazotization and coupling reactions used in dye chemistry. The presence of the electron-donating ethoxy substituent influences its reactivity and dyeing behavior relative to unsubstituted aniline and other substituted anilines. It is generally handled and stored under standard conditions suitable for aromatic amines, with attention to avoiding exposure to oxidizing environments.

Safety and handling: Like other aromatic amines, 4-ethoxyaniline can be irritating to skin, eyes, and the respiratory tract and may pose health hazards if inhaled or ingested. It should be handled in a well-ventilated area, with appropriate personal protective equipment and proper waste disposal. Storage should keep the material away from strong oxidizers and sources of ignition, in accordance with relevant safety regulations.