3phenylchromen4one

3-phenylchromen-4-one, also named 3-phenylchromone, is an organic compound belonging to the chromone family. It features a chromone core—an aromatic benzopyran-4-one fused ring system—with a phenyl group at the 3-position. This substitution pattern places the molecule as a 3-aryl chromone derivative, closely related to the flavone skeleton that is widely studied in medicinal chemistry and natural product research.

Chemical information and structure: The compound has a molecular formula of C15H10O2 and a molecular weight of approximately 222.24 g/mol. Its structure consists of a benzene ring fused to a pyranone ring, with the phenyl substituent attached at C3 of the chromone framework.

Occurrence and synthesis: 3-phenylchromen-4-one is mainly prepared synthetically as a versatile building block for chromone- and flavonoid-related chemistry. It is not broadly documented as a common natural product, though chromone scaffolds appear in various plant-derived compounds. Numerous synthetic routes exist to access 3-aryl chromones, reflecting the compound’s utility as a precursor for more complex chromone derivatives.

Applications and research: As a chromone derivative, 3-phenylchromen-4-one serves as a scaffold in medicinal chemistry and pharmaceutical research. Derivatives of the chromone framework are explored for a range of biological activities, and the 3-phenyl variant is used to study structure-activity relationships and to develop new pharmacophores. In addition, chromone compounds are examined in materials science for potential photophysical and electronic properties, with specific results varying by study.

See also: Chromone; Flavone; Chromones in medicinal chemistry.