3alphaHSD
3alphaHSD refers to 3-alpha-hydroxysteroid dehydrogenase. This is an enzyme that belongs to the short-chain dehydrogenase/reductase (SDR) superfamily. Its primary function is to catalyze the oxidation of 3-alpha-hydroxysteroids to their corresponding 3-keto steroid derivatives. This enzymatic activity is crucial in various metabolic pathways within living organisms.
The enzyme plays a significant role in steroid hormone metabolism. It is involved in the interconversion of
In humans, 3alphaHSD enzymes are encoded by a family of genes, with different isoforms expressed in various