3Chlorobenzaldehyde

3-Chlorobenzaldehyde is an organic compound that belongs to the class of aromatic aldehydes. It is characterized by the presence of a formyl group (-CHO) attached to a benzene ring, which is also substituted with a chlorine atom at the meta position. The molecular formula of 3-chlorobenzaldehyde is C7H5ClO, and its molecular weight is approximately 140.57 g/mol.

This compound is a colorless to pale yellow liquid with a pungent, aldehydic odor. It is sparsely soluble in water but miscible with most organic solvents, such as ethanol, ether, and chloroform. 3-Chlorobenzaldehyde is primarily used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and dyestuffs. It serves as a crucial building block in the production of certain drugs, including some antimalarial and anti-inflammatory agents.

The preparation of 3-chlorobenzaldehyde typically involves the chlorination of benzaldehyde, followed by a rearrangement reaction to position the chlorine atom at the meta position relative to the formyl group. Alternatively, it can be synthesized through the formylation of chlorobenzene using specific reagents and catalysts.

Handling 3-chlorobenzaldehyde requires caution, as it is considered a hazardous material. It is irritating to the eyes, skin, and respiratory tract. Prolonged exposure can lead to more severe health effects. Appropriate personal protective equipment (PPE) and proper ventilation should be used when handling this compound. Additionally, it should be stored in a cool, well-ventilated area away from sources of ignition and incompatible substances.

In summary, 3-chlorobenzaldehyde is a valuable intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries. Its unique structure and reactivity make it a useful component in the production of various commercially important compounds. However, due to its hazardous nature, proper safety measures must be observed when handling this substance.