2q35

2q35 is a chromosomal region located on the long arm of chromosome 2. Specifically, it refers to band 35 of the q arm. Chromosomes are structures found inside the nucleus of cells that carry genetic information in the form of genes. The long arm of a chromosome is denoted by the letter 'q', and numerical designations (like 35) refer to progressively finer subdivisions of the chromosome as seen under a microscope.

Genetic variations or alterations within the 2q35 region can be associated with various health conditions. These alterations can include deletions, duplications, translocations, or other structural rearrangements. Research has identified specific genes within this locus that play roles in development and cellular function. When these genes are disrupted due to changes in the 2q35 region, it can lead to a range of phenotypes.

Studies have linked abnormalities in 2q35 to developmental disorders, intellectual disability, and certain congenital anomalies. The precise impact of changes in this region often depends on the specific genes affected and the nature of the genetic alteration. Genetic testing and cytogenetic analysis are used to identify these chromosomal abnormalities. Ongoing research continues to explore the specific genes and functions within 2q35 and their contribution to human health and disease.