2aminomethylophenol

2-aminomethylophenol, also known as o-aminomethylphenol or 2-(aminomethyl)phenol, is an organic compound belonging to the class of aromatic amines and phenols. Its chemical structure consists of a phenol ring (a benzene ring with a hydroxyl group) substituted with an aminomethyl group (-CH₂NH₂) at the ortho position relative to the hydroxyl group. The compound has the molecular formula C₇H₉NO and a molar mass of approximately 123.15 g/mol.

This colorless to pale yellow crystalline solid is soluble in water and many organic solvents, including alcohols and ethers. It exhibits both acidic and basic properties due to the presence of the hydroxyl and amino functional groups, respectively. The compound is sensitive to oxidation and can darken upon exposure to air or light.

2-aminomethylophenol is primarily used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and specialty chemicals. It plays a role in the production of certain dyes, antioxidants, and pharmaceuticals such as some types of analgesics and local anesthetics. Additionally, it may be employed in the manufacture of resins and other polymeric materials.

Safety considerations are important when handling 2-aminomethylophenol, as it can be irritating to the skin, eyes, and respiratory tract. Proper protective equipment, such as gloves, goggles, and lab coats, should be used during handling. The compound should be stored in a cool, dry place, away from strong oxidizing agents and incompatible substances, and under inert atmospheric conditions to prevent degradation.

Due to its reactivity, 2-aminomethylophenol is typically handled in controlled laboratory settings or industrial environments with appropriate safety measures in place. Research and industrial applications continue to explore its potential in various chemical synthesis pathways.