2Methylbenzaldehyde

2-Methylbenzaldehyde, also known as o-tolualdehyde, is an organic compound with the chemical formula C8H8O. It is a derivative of benzaldehyde, where a methyl group (-CH3) is substituted at the ortho position (2-position) of the phenyl ring. This compound is a colorless liquid with a strong, characteristic odor. It is primarily used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds.

The synthesis of 2-methylbenzaldehyde typically involves the formylation of toluene using reagents such as carbon monoxide and hydrogen in the presence of a catalyst, or the oxidation of 2-methylbenzyl alcohol. The compound can also be prepared through the reaction of 2-methylbenzoic acid with formic acid or formamide.

2-Methylbenzaldehyde is a versatile building block in organic synthesis. It can undergo various reactions, including aldol condensations, cross-coupling reactions, and reductions, to form a wide range of products. Its reactivity and structural features make it valuable in the development of new drugs and other chemical entities.

In terms of safety, 2-methylbenzaldehyde is flammable and should be handled with care. It is also considered to be a potential carcinogen, and its use is regulated in some countries. Proper personal protective equipment and safety measures should be employed when handling this compound.