1phenylpropan1one

1-Phenylpropan-1-one, also known as propiophenone, is an organic compound with the chemical formula C9H10O. It is a ketone with a phenyl group and a propyl group attached to the carbonyl carbon. Propiophenone is a colorless liquid with a sweet, floral odor. It is sparingly soluble in water but soluble in most organic solvents.

Propiophenone can be synthesized through several methods. One common route is the Friedel-Crafts acylation of benzene with propionyl chloride. It can also be prepared by the oxidation of 1-phenylpropan-1-ol or by the Grignard reaction between phenylmagnesium bromide and propionitrile.

This compound finds applications as a building block in organic synthesis. It is used in the production of pharmaceuticals, fragrances, and other fine chemicals. For instance, it serves as a precursor in the synthesis of certain antidepressant drugs and as an intermediate in the manufacturing of insecticides. Its characteristic aroma also leads to its inclusion in some perfume formulations. Propiophenone is generally considered to have low toxicity, though prolonged or excessive exposure should be avoided.