1Methyl1Hindole

1-Methyl-1H-indole, also known as N-methylindole, is a heterocyclic organic compound with the chemical formula C9H9N. It is an indole derivative where a methyl group is attached to the nitrogen atom at the 1-position of the indole ring. The indole ring system consists of a six-membered benzene ring fused to a five-membered pyrrole ring. In 1-methyl-1H-indole, the nitrogen atom of the pyrrole ring bears a methyl substituent.

This compound typically appears as a colorless to pale yellow liquid with a characteristic odor. It is sparingly soluble in water but miscible with many organic solvents like ethanol, ether, and chloroform. The presence of the methyl group on the nitrogen atom influences its chemical properties compared to unsubstituted indole. For instance, it affects the electron density distribution within the aromatic system and alters its reactivity in various chemical transformations.

1-Methyl-1H-indole can be synthesized through several methods, including the methylation of indole itself using methylating agents such as methyl iodide or dimethyl sulfate under basic conditions. It also finds applications as a building block in organic synthesis, particularly in the preparation of more complex molecules. Its derivatives are explored in research for potential pharmacological activities, though 1-methyl-1H-indole itself is not typically a finished pharmaceutical product.