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Troponin is a complex of three regulatory proteins, including troponin C, troponin I, and troponin T, found in muscles. It plays a crucial role in the regulation of muscle contraction by interacting with actin and tropomyosin. Troponin acts as a receptor for calcium ions, binding to them and undergoing a conformational change that determines the accessibility of certain regions of actin to myosin heads.
Troponin C binds to calcium ions, causing a structural change that shifts tropomyosin and blocks the interaction
Troponin is composed of three subunits, each of which has distinct functions. Troponin C is responsible for
Research into troponin has shed light on a range of diseases and conditions associated with it, including