triazoler
Triazoles are five‑membered heterocyclic compounds containing three consecutive nitrogen atoms. The parent structure consists of a ring with formula C2H3N3, and the ring can be either 1,2,3‑triazole or 1,2,4‑triazole depending on the positions of the nitrogen atoms. These heterocycles are aromatic, possessing two pairs of electrons that contribute to the ring’s delocalization, which imparts relative stability and reactivity.
The synthesis of triazoles is commonly achieved through cycloaddition reactions. The Huisgen 1,3‑dipolar cycloaddition between organic
Triazoles serve as key structural motifs in pharmaceuticals, agrochemicals, and materials science. In medicine, 1,2,3‑triazole derivatives
Safety considerations for triazole compounds vary widely. While many pharmaceutical triazoles are non‑toxic at therapeutic doses,