translationinitiated
Translation initiated refers to the starting point of the process by which a sequence of nucleotides in messenger RNA (mRNA) is used as a template to synthesize a protein. This crucial step in gene expression occurs in the cytoplasm of the cell on ribosomes. The initiation phase involves the assembly of the ribosome on the mRNA molecule, the positioning of the initiator tRNA carrying the first amino acid, and the formation of the first peptide bond.
The process typically begins with the small ribosomal subunit binding to the mRNA. In eukaryotes, this binding