somattiselle

Somattiselle, also known as somatostatin, is a peptide hormone that plays a crucial role in the regulation of various physiological processes in the body. It was first isolated from the hypothalamus of the pig in 1973 and is named after the Greek words "soma," meaning body, and "stasis," meaning standing still, reflecting its inhibitory effects on various bodily functions.

Somattiselle is produced by the delta cells of the pancreas and is released in response to increased blood glucose levels. It acts as an antagonist to growth hormone, inhibiting its release from the pituitary gland. This inhibitory effect helps to maintain glucose homeostasis by reducing the body's glucose uptake and utilization.

In addition to its role in glucose regulation, somattiselle also has a wide range of other physiological effects. It inhibits the release of several other hormones, including insulin, glucagon, gastrin, and secretin. It also has a direct effect on the gastrointestinal tract, slowing down gastric emptying and reducing gastric acid secretion. Somattiselle also has a neuroprotective effect, protecting neurons from damage and promoting their survival.

Somattiselle is used clinically as a diagnostic tool to assess pancreatic function. It is also used in the treatment of conditions such as acromegaly, where it helps to control the excessive growth hormone production. Somattiselle is available in various forms, including injectable solutions and oral tablets.

Despite its beneficial effects, somattiselle can also have side effects, including nausea, vomiting, diarrhea, and abdominal pain. It is important to use somattiselle under the guidance of a healthcare professional to minimize these risks and ensure its safe and effective use.